Reductive N-Alkylation of Nitroarenes: A Green Approach for the N-Alkylation of Natural Products
نویسندگان
چکیده
منابع مشابه
Direct one-pot reductive N-alkylation of nitroarenes by using alcohols with supported gold catalysts.
The formation of C N bonds is one of the most important transformations in chemistry because nitrogen-containing compounds, particularly amines and their derivatives, are versatile building blocks for various organic molecules and essential precursors to a variety of biologically active compounds. Although several methods are known for the synthesis of C N bonds, preparation under mild and wast...
متن کاملCatalytic reductive N-alkylation of amines using carboxylic acids.
We report a catalytic reductive alkylation reaction of primary or secondary amines with carboxylic acids. The two-phase process involves silane mediated direct amidation followed by catalytic reduction.
متن کاملMechanochemical N-alkylation of imides
The mechanochemical N-alkylation of imide derivatives was studied. Reactions under solvent-free conditions in a ball mill gave good yields and could be put in place of the classical solution conditions. The method is general and can be applied to various imides and alkyl halides. Phthalimides prepared under ball milling conditions were used in a mechanochemical Gabriel synthesis of amines by th...
متن کاملThe Selective N-Alkylation of Monoethanolamine
Alkyl derivatives of MEA are used in the production of surfactants, dyes, in the manufacture of drugs as a buffer substance and for the stabilization of emulsions, in the manufacture of herbicides, cosmetics, antihistamines, are also of practical interest [1]. It is widely known also as useful “acid” gases (H2S, CO2, SO2, etc.) as absorbents in the process of cleaning process for gases in oil r...
متن کاملThe Selective N-Alkylation of Monoethanolamine
Alkyl derivatives of MEA are used in the production of surfactants, dyes, in the manufacture of drugs as a buffer substance and for the stabilization of emulsions, in the manufacture of herbicides, cosmetics, antihistamines, are also of practical interest [1]. It is widely known also as useful “acid” gases (H2S, CO2, SO2, etc.) as absorbents in the process of cleaning process for gases in oil r...
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ژورنال
عنوان ژورنال: The Journal of Organic Chemistry
سال: 2012
ISSN: 0022-3263,1520-6904
DOI: 10.1021/jo300303d